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Surveying extant communities of psychedelic microdosers allows for the creation of a preliminary qualitative taxonomy that could inform future intervention research. This taxonomy identifies recurring themes in perceived challenges, including physiological discomfort (disrupted senses, temperature dysregulation, numbing/tingling), cognitive interference, self-interference (dissociation, depersonalization), and restlessness. The data suggest that future studies should target these constructs in order to reduce reported difficulties.